Defining Mesothelioma and Its Causes Mesothelioma is a rare and aggressive form of cancer that primarily affects the lining of the lungs, known as the pleura, though it can also occur in the lining of the abdomen or heart. Its development is strongly linked to the inhalation or ingestion of asbestos fibers, which can cause damage to the mesothelial cells and lead to cancerous mutations over time. The primary causes of mesothelioma include: Asbestos Exposure: The inhalation or ingestion of asbestos fibers is the most significant risk factor for developing mesothelioma. These fibers can become lodged in the mesothelial lining,...